鹽-神經(jīng)系統(tǒng)-血壓
來源:滬江聽寫酷
2012-01-20 12:44
the article is relaed to something about absorption of salt with adrenaline and hypertesion according to Haralambos Gavras at the Boston University School of Medicine
People with high blood pressure are often told to watch the salt. And it’s long been thought that hypertension related to excess salt is caused by the salt increasing the volume of the blood. Which in turn puts added pressure on the blood vessel walls. But going back to the 1960s and ‘70s, some researchers thought that the salt might be having a different effect.
Now long-time hypertension researchers Irene and Haralambos Gavras at the Boston University School of Medicine have analyzed the studies in the field and published a review article explaining what they think salt’s role really is: it stimulates the sympathetic nervous system to produce adrenalin. And it’s the adrenalin that constricts the arteries and causes the high blood pressure, not excess fluid volume. The review is in the Journal of Hypertension.
Physicians have accepted a nervous system involvement in hypertension that’s bad enough to cause kidney failure. Fluid-decreasing diuretics are a common treatment in those severe cases. This new analysis implies that researchers should look for additional hypertension treatments that focus on the nervous system.
高血壓患者需要限制攝取鹽分。很長一段時(shí)間人們都以為攝取過多鹽分導(dǎo)致血液增多才是引起高血壓癥的原因。因?yàn)檠涸龆鄷?huì)增加血液對血管壁的壓力。但若回顧六七十年代的一些研究,一些研究人員發(fā)現(xiàn)鹽分也許還有一些其它的作用。
現(xiàn)在,波士頓大學(xué)藥學(xué)研究者Irene 和Haralambos Gavras長期從事對高血壓研究,他們已經(jīng)分析研究并發(fā)表一篇綜述文章用以解釋他們認(rèn)為鹽分對人體真正的作用,那就是:鹽類刺激交感神經(jīng)系統(tǒng)產(chǎn)生腎上腺素。而腎上腺素使主動(dòng)脈收縮從而引發(fā)高血壓,而非如前所述由于液體體積增多而引起血壓高。這篇綜述已經(jīng)發(fā)表在《高血壓》雜志上。
生理學(xué)家已經(jīng)承認(rèn)高血壓狀態(tài)下的神經(jīng)系統(tǒng)會(huì)起到負(fù)面作用足以導(dǎo)致腎衰竭。促使體液減少的利尿劑是目前對嚴(yán)重高血壓病例的一種常用治療方法。這項(xiàng)最新的分析研究結(jié)果提示研究人員們應(yīng)該尋找與神經(jīng)系統(tǒng)相關(guān)的其它高血壓癥治療方法。
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