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For those of you who love a tall tale, the list of genetic variations that determine human height has just experienced a growth ____1_____. The findings were published by the journal Nature.
Height has a lot to do with genetics. If your parents don’t need a step stool to reach the top shelf, you’re probably ____2____, too. About 80 percent of height is due to DNA. The rest depends on diet and other environmental factors.
In the new study, researchers analyzed DNA from more than 180,000 people, looking for genetic differences that ____3____ height. The scientists, part of a consortium called the Genetic Investigation of Anthropocentric Traits (or GIANT), found 180 gene regions that govern how tall we get.
The variants, 100 of which were previously unknown, aren’t sprinkled randomly around the genome. Many ____4____ sets of genes associated with growth, including 21 variants found in or near genes that regulate the building of bone.
Of course even this new list comes up short. The 180 variations account for only 10 percent of the difference between a jockey and a jumpshooter. But the work shows that research into complex genetic traits is ____5____.
spurt right up there dictate cluster around getting off the ground
對(duì)那些喜歡以高個(gè)子為主角的奇談故事的人來(lái)說(shuō),決定人類身高的基因變異種類突然井噴般增加了很多。這個(gè)發(fā)現(xiàn)被刊登在《自然》雜志里。 身高和遺傳相關(guān)。如果你的父母不需要踏腳凳就可以摸到架子的最上層,你可能一樣做得到。身高80%和DNA有關(guān),其余20%則和飲食以及其他環(huán)境因素有關(guān)。 在新的研究中,研究人員分析了一百八十多萬(wàn)人的DNA,以尋找決定身高的基因變異。人類性狀遺傳研究中心的企業(yè)集團(tuán)(GIANT)的科學(xué)家找到了180個(gè)掌管身高的基因區(qū)。 這些基因變異當(dāng)中,有100種是之前聞所未聞的。它們并不是隨便分布在染色體組當(dāng)中,其中有很多幾種分布在和發(fā)育有關(guān)的兩組基因里,包括21種在和骨骼生長(zhǎng)有關(guān)的基因里面或者附近的不同基因。 當(dāng)然,這些新的基因變異種類還有不足。想要知道職業(yè)賽馬騎士和籃球跳投選手身高不同的原因,這180種基因變異也僅能為你提供十分之一的答案。但是目前的工作顯示,關(guān)于復(fù)雜基因性狀研究的進(jìn)展非常順利。