壞消息:肥胖不光丑,而且還致癌
作者:滬江英語(yǔ)
2019-01-05 12:00
2019.01.05
周六 Saturday
clog?/kl?g/?
v. 阻塞
A?new discovery could explain why obese people are more likely to develop cancer, scientists say.?A type of cell the body uses to destroy cancerous tissue gets?clogged?by fat and stops working, the team, from Trinity College Dublin, found.
科學(xué)家們表示,現(xiàn)在有一項(xiàng)新研究可能可以解釋為什么肥胖的人更可能得癌癥。一個(gè)來(lái)自都柏林三一學(xué)院的團(tuán)隊(duì)發(fā)現(xiàn),我們身體用來(lái)破壞癌變組織的一種細(xì)胞會(huì)被脂肪堵塞并停止工作。
Obesity?is the biggest preventable cause of cancer in the UK after smoking, Cancer Research UK says. And more than one in 20 cancer cases - about 22,800 cases each year in the UK - are caused by excess body weight.
據(jù)英國(guó)的癌癥研究學(xué)會(huì)說(shuō),肥胖在英國(guó)是僅次于吸煙的可預(yù)防型癌癥原因。而且有超過(guò)1/20的癌癥案例都是由超重引起的,這在英國(guó)每年就有差不錯(cuò)22800例。
Experts?already suspected fat sent signals to the body that could both damage cells, leading to cancer, and increase the number of them. Now, the Trinity scientists have been able to show, in Nature Immunology journal, how the body's cancer-fighting cells get clogged by fat.
專(zhuān)家們以前就在懷疑脂肪給身體傳遞的一些信號(hào)會(huì)損害我們的細(xì)胞、引發(fā)癌癥并增加癌變細(xì)胞的數(shù)量。而跟根這次據(jù)三一學(xué)院的科學(xué)家在《自然免疫學(xué)》期刊上發(fā)表的研究,他們已經(jīng)能夠展示出脂肪是如何堵塞那些抗癌細(xì)胞的了。
And?they hope to be able to find drug treatments that could restore these "natural killer" cells' fighting abilities.
他們希望能找出一種藥物療法來(lái)幫這些“天生的癌癥殺手細(xì)胞”恢復(fù)戰(zhàn)斗能力。
Prof?Lydia Lynch said: "A compound that can block the fat uptake by natural killer cells might help. We tried it in the lab and found it allowed them to kill again. But arguably a better way would be to lose some weight - because that is healthier for you anyway."
Lydia Lynch教授說(shuō):“有一種化合物可以防止這些癌癥殺手細(xì)胞吸收脂肪,我們可能可以用它。我們已經(jīng)在實(shí)驗(yàn)室里試過(guò)這種物質(zhì)了,發(fā)現(xiàn)它讓癌癥殺手細(xì)胞得以重新開(kāi)始擊殺。不過(guò)更好的辦法應(yīng)該還是減肥,畢竟那能讓你更健康?!?/div>
Dr?Leo Carlin, from the Cancer Research UK Beatson Institute, said: "Although we know that obesity increases the risk of 13 different types of cancer, we still don't fully understand the mechanisms underlying the link.
來(lái)自英國(guó)癌癥研究學(xué)會(huì)比斯頓研究所的Leo Carlin博士說(shuō):“雖然我們知道肥胖能夠提升13種不同癌癥的發(fā)病率,但我們還沒(méi)有完全明白具體的機(jī)制?!?/div>
"This?study reveals how fat molecules prevent immune cells from properly positioning their tumour-killing machinery, and provides new avenues to investigate treatments. A lot of research focuses on how tumours grow in order to find metabolic targets to stop them, so this is a reminder that we should consider the metabolism of immune cells too."
“而這次的研究讓我們明白了脂肪分子是如何阻礙免疫細(xì)胞的抗癌機(jī)制的,也為我們尋找相關(guān)治療方法指明了新方向。已經(jīng)有很多研究著眼于腫瘤的生長(zhǎng),以希望能找到從新陳代謝角度阻止他們的方法;而我們這次研究則提醒我們或許也應(yīng)該研究一下免疫細(xì)胞的新陳代謝機(jī)制?!?/div>
?
今日詞匯
clog?/kl?g/?
v. 阻塞
?
這個(gè)詞表示“阻塞”、“堵塞”。
要表示“阻塞……”直接用?clog sth.
例如:
Dirt has clogged the pores.
塵垢堵塞了毛孔。
如果要說(shuō)“用……阻塞……”,需要用上clog sth. with sth.
例如:
The narrow streets were clogged with traffic.
當(dāng)時(shí)那些狹窄的小街都被交通堵塞了。
它也有名詞的含義,不過(guò)意思是“木屐”或者“木底鞋”。
?
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