【探索世界】基因外遺傳現(xiàn)象(23/30)
Hints:
Olov Bygren
er, em,
stumbled on
Markus Pembrey
longevity
indicator
epigenetics
diabetes
trans-generational
51’’左右處有一破折號(hào)( -- )
Olov Bygren was looking to see if poor nutrition had an effect on health when he stumbled on something curious. It appeared that a famine could affect people almost 100 years later even if they never suffered a famine themselves. He wanted to know how this might be possible? So he asked Markus Pembrey.
Olov first reported that the food supply of the ancestors was affecting the longevity or, or mortality rate of the grandchildren. Em, so I was very excited. I responded immediately.
Pembrey had a hunch that the incidence of one disease -- diabetes, might be an indicator that epigenetics was involved.
Specifically I wanted to know the results of the diabetes because this was the one that I thought might involve the imprinting.
So Olov trod the records for any death due to diabetes and then looked back to see if there was anything unusual about the diet of their grandparents.
Er, a few months later, he e-mailed me to say that indeed they had shown a strong association, er, between the, er, em, food supply of the father's father, and the chance of diabetes being mentioned on the death certificate of the grandchild. Er, so of course I was really rather excited about that because it really did look as if there was some trans-generational effect going on there.
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